Time in range targets for standardized data interpretation and decision making in diabetes
Based on data from randomized controlled trials, internationally accepted clinical guidelines have been published for the interpretation of data and to establish clear and easy-to-understand targets for continuous glucose monitoring (CGM) metrics that diabetes care teams and individuals with diabetes can work together to achieve.
Authors: Tadej Battelino, Klemen Dovč
In months of dedicated preparations, the researchers from the University of Ljubljana Faculty of Medicine (Tadej Battelino, Klemen Dovč) together with the most distinguished diabetologists and scientists from prestigious academic institutions in 14 countries around the globe gathered to create guidelines for CGM Time-in-Range goals that complement widely accepted indicators of glycemic control, such as glycosylated haemoglobin. The panel recommended a standardized CGM report incorporating key CGM metrics and targets along with a 14-day composite glucose profile to be an integral component of clinical decision making. The CGM targets and standardized profile proposed by the International Consensus may facilitate the routine use of CGM and improve clinical outcomes of diabetes management. The reporting, presentation, and visualization of CGM data now greatly facilitate the communication between health care professionals and individuals with diabetes, either type 1 or type 2 diabetes, older, at high risk for severe hypoglycemia, or for pregnanancy complicated with diabetes, and provide guidance to utilize, interpret and report CGM data in both routine clinical care and research.
The final document was sent for assessment by the most eminent professional organisations in the field of diabetes. This international consensus report was officially endorsed by the American Diabetes Association, American Association of Clinical Endocrinologists, American Association of Diabetes Educators, European Association for the Study of Diabetes, Foundation of European Nurses in Diabetes, International Society for Pediatric and Adolescent Diabetes, JDRF and the Pediatric Endocrine Society. To ensure the recommendations are generalizable and comprehensive, the consensus panel included individuals living with diabetes and had international representation from physicians and researchers from all geographic regions.
Publication of the manuscript was accompanied by an oral presentation and far-reaching press conference at the annual American Diabetes Association meeting. Just over two months since its publication, the paper has 14 citations and an h-index of 268.
Source: Battelino T., Danne T., Bergenstal R., Amiel S. A., Beck R., Biester T., Bosi, E., Buckingham B., Cefalu, W. T., Close K. L., Dovč K., et al. Clinical targets for continuous glucose monitoring data interpretation: recommendations from the international consensus on time in range. Diabetes care, 42 (2019), 1593-1603.
Presentation of glucose target values for time in range by individual groups.
Source: Battelino T., Danne T., Bergenstal R., Amiel S. A., Beck R., Biester T., Bosi E., Buckingham B., Cefalu W. T., Clo, K. L., Dovč K., et al. Clinical targets for continuous glucose monitoring data interpretation: recommendations from the international consensus on time in range. Diabetes care, 42 (2019), 1593-1603.