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Amniotic membrane-based antimicrobial agent

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Areas

Health

Fields of use

Healthcare-Medical Science

Current state of technology

Laboratory tested; preclinical

Intellectual property

EP 20704206.0, PCT/EP2020/052288

Developed by

University of Ljubljana, Medical Faculty

Reference

821-19/2018

Contact

Knowledge Transfer Office UL


Gabriela Droga Mazovec
Phone: +386 70 538 284
E-mail: gospodarstvo@uni-lj.si

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Background

During the years 2000 and 2015, the use of antibiotics worldwide increased for 65%. Epidemiological studies showed the correlation between the increasing use of antibiotics and the emergence and spreading of bacteria, resistant to antibiotics. The studies show there is a great need for discovery and development of novel antimicrobials.

Description of invention

The developed mammalian amniotic membrane homogenate can be used as an antimicrobial agent. The preparation of which runs through a well-determined procedure so that its antibacterial characteristics remain intact.

Main advantages

Antimicrobial activity of amniotic membrane has been proven against several bacteria, namely Escherichia coli, Staphylococcus aureus,  Enterobacter sp., Klebsiella pneumoniae, Staphylococcus saprophyticus and others. The preparation procedure is simple and cost-effective and the homogenate presents a high efficacy rate.